Medicina Ricerca in Oncologia.
“Six patterns of homeopathy use in integrative oncology: A qualitative study (TOUCAN)”
Pubblicato su Advances in Integrative Medicine .
A settembre 2024, nell’ambito della ricerca scientifica in omeopatia, è stato pubblicato un nuovo studio intitolato Six patterns of homeopathy use in integrative oncology: A qualitative study (TOUCAN) .
La ricerca – pubblicata sulla rivista internazionale peer reviewed “Advances in Integrative Medicine” – è stata realizzata in Francia e ha consentito di identificare almeno sei ragioni pratiche per cui i pazienti con cancro al seno si rivolgono all’omeopatia nell’ambito dell’oncologia integrativa (IO).
Queste ragioni dipendono dalla rappresentazione della cura nel suo complesso, insieme alla disponibilità, all’accessibilità, all’efficacia, ai benefici e allo sforzo richiesto da questa e da altre terapie – sia convenzionali che di supporto – utilizzate dal paziente.
Nello specifico i ricercatori hanno posto in evidenza i diversi modi in cui i pazienti utilizzano l’omeopatia in relazione alle terapie convenzionali e di supporto in oncologia integrativa:
- come terapia aggiuntiva alle cure convenzionali e di supporto,
- come terapia da integrare con altre terapie di supporto,
- in sostituzione della terapia di supporto,
- in sostituzione dei farmaci di supporto,
- come opzione non adatta a sostituire tutte le terapie di supporto,
- come unica opzione di supporto disponibile in alcune situazioni.
Da questa analisi deriva in modo chiaro il messaggio che i medici dovrebbero valutare più frequentemente i diversi usi dell’omeopatia nelle cure di supporto.
L’omeopatia, quindi, il trattamento convenzionale del cancro, gli operatori sanitari e le terapie di supporto formano un insieme coeso.
La ricerca è il risultato della collaborazione scientifica di ricercatori provenienti dai seguenti Centri :
- Patient-Reported Outcomes Unit (PROQOL), INSERM UMR 1123, Paris Cité University, France;
- Health Economics Clinical Trial Unit (URC-ECO), Hotel-Dieu Hospital, AP-HP, Paris, France;
- EMEDE Consulting & Axial, Boulogne-Billancourt, France;
- Department of Oncology Radiotherapy, Troyes hospital, Troyes, France;
- Andrée Dutreix Institute, Dunkerque, France.
Nelle conclusioni del lavoro, i ricercatori scrivono:
“Pochi studi hanno esplorato la combinazione di terapie di supporto o CAM, il che può sollevare dubbi sul loro ruolo nell’oncologia integrativa (integrative oncology – IO). Il nostro studio, che tratta l’omeopatia come un trattamento di supporto e complementare, rivela che, nella pratica riportata, l’omeopatia è stata utilizzata accanto alle cure convenzionali e di supporto, ha integrato altre terapie di supporto, ha sostituito i farmaci di supporto e, in alcuni casi, è stata l’unica opzione disponibile. Tuttavia, non poteva sostituire tutte le altre terapie di supporto. Le aspettative dei pazienti nei confronti dell’omeopatia, che si allineano a quelle di altre forme di CAM, ne influenzano l’utilizzo. Queste aspettative sono modellate dalla rappresentazione complessiva della cura, così come dalla disponibilità, dall’accessibilità, dall’efficacia, dai benefici e dall’impegno richiesto da altri trattamenti, sia convenzionali che di supporto, che il paziente utilizza. I clinici e i ricercatori dovrebbero considerare spesso la probabilità che i pazienti utilizzino l’omeopatia nell’oncologia integrativa (IO), per comprenderne appieno i significati e le motivazioni sottostanti. Dato l’uso diffuso dell’omeopatia in vari modi e la mancanza di prove solide, sembra fondamentale condurre valutazioni comparative per posizionarla meglio in una strategia di oncology integrative (IO)”.
Interessante anche la bibliografia di riferimento pubblicata in calce alla ricerca:
References
[1] A.N. Giaquinto, H. Sung, K.D. Miller, J.L. Kramer, L.A. Newman, A. Minihan, et al.
Breast cancer statistics, 2022 CA A Cancer J. Clin., 72 (6) (2022), pp. 524-541[2] Panorama des cancers en France [Internet]. Institut National du Cancer; 2022 [2023-01-16]. Available at: 〈https://www.e-cancer.fr/Patients-et-proches/Les-cancers/Cancer-du-sein/Quelques-chiffres〉.
[3] P. Mokhtari-Hessari, A. Montazeri – Health-related quality of life in breast cancer patients: review of reviews from 2008 to 2018
Health Qual. Life Outcomes, 18 (1) (2020), p. 338[4] C.N. Rittenberg, J.L. Johnson, G.M. Kuncio – An oral history of MASCC, its origin and development from MASCC’s beginnings to 2009
Support Care Cancer, 18 (6) (2010), pp. 775-784[5] Circulaire DHOS/SDO no 2005-101 du 22 février 2005 relative à l’organisation des soins en cancérologie [Internet]. SANH0530076C 2005. Available at: 〈https://solidarites-sante.gouv.fr/fichiers/bo/2005/05-03/a0030034.htm〉.
[6] Cancers du sein – Du diagnostic au suivi [Internet]. [2023-07-24]. Available at: 〈https://www.e-cancer.fr/Expertises-et-publications/Catalogue-des-publications/Cancers-du-sein-Du-diagnostic-au-suivi〉.
[7] C.M. Witt, L.G. Balneaves, M.J. Cardoso, L. Cohen, H. Greenlee, P. Johnstone, et al.
A comprehensive definition for integrative oncology
JNCI Monogr., 2017 (52) (1 nov 2017)
〈http://academic.oup.com/jncimono/article/doi/10.1093/jncimonographs/lgx012/4617827〉[8] B. Mastroianni, M. Lochmann, M. Girodet, J.Y. Blay, V. Christophe, G. Chvetzoff
L’oncologie intégrative: état des lieux et place d’une consultation dédiée dans un centre de lutte contre le cancer
Bull. du Cancer, 109 (12) (2022), pp. 1308-1314[9] A. Molassiotis, P. Fernandez-Ortega, D. Pud, G. Ozden, J.A. Scott, V. Panteli, et al.
Use of complementary and alternative medicine in cancer patients: a European survey
Ann. Oncol., 16 (4) (2005), pp. 655-663[10] M. Horneber, G. Bueschel, G. Dennert, D. Less, E. Ritter, M. Zwahlen
How many cancer patients use complementary and alternative medicine: a systematic review and metaanalysis
Integr. Cancer Ther., 11 (3) (2012), pp. 187-203[11] P. Lapidari, N. Djehal, J. Havas, A. Gbenou, E. Martin, C. Charles, et al.
Determinants of use of oral complementary-alternative medicine among women with early breast cancer: a focus on cancer-related fatigue
Breast Cancer Res. Treat., 190 (3) (2021), pp. 517-529[12] E. Garrido, V. Santoro Lamelas, M. Pla, R. Manzanera, X. Bargallo, R. Puigpinos-Riera, et al.
Use of non-conventional therapies in a cohort of women with breast cancer (DAMA cohort) in Barcelona (Spain). A mixed-methods study
Eur. J. Integr. Med., 37 (2020), Article 101148[13] M. Saghatchian, C. Bihan, C. Chenailler, C. Mazouni, S. Dauchy, S. Delaloge
Exploring frontiers: use of complementary and alternative medicine among patients with early-stage breast cancer
Breast, 23 (3) (2014), pp. 279-285[14] S. Lettner, K.A. Kessel, S.E. Combs
Complementary and alternative medicine in radiation oncology Survey of patients’ attitudes
Strahlenther. Onkol., 193 (5) (2017), pp. 419-425[15] M. Joël, V. Rubio
Pratiques non conventionnelles et articulation des soins en cancérologie. Le rôle actif des patients
Sci. Soc. Et. Santé, 33 (4) (2015), pp. 73-97[16] M. Vidal, C. Carvalho, R. Bispo
Use of complementary and alternative medicine in a sample of women with breast cancer
SAGE Open, 3 (3) (2013)[17] S. Träger-Maury, C. Tournigand, F. Maindrault-Goebel, P. Afchain, A. de Gramont, M.L. Garcia-Larnicol, et al.
Use of complementary medicine by cancer patients in a French oncology department
Bull. Cancer, 94 (11) (2007), pp. 1017-1025[18] Cathebras P. Le recours aux médecines parallèles observé depuis l’hôpital: banalisation et pragmatisme. In: Benoist J., éditeur. Soigner au pluriel Essais sur le pluralisme médical. Paris: Les Éditions Karthala; 1996.
[19] J. Medioni, D. Scimeca, Y.L. Marquez, E. Leray, M. Dalichampt, N. Hoertel, et al.
Benefits of homeopathic complementary treatment in patients with breast cancer: a retrospective cohort study based on the french nationwide healthcare database
Clin. Breast Cancer, 23 (1) (2023), pp. 60-70[20] T. Ashikaga, K. Bosompra, P. O’Brien, L. Nelson
Use of complementary and alternative medicine by breast cancer patients: prevalence, patterns and communication with physicians
Support Care Cancer, 10 (7) (2002), pp. 542-548[21] O. Schmitz
Soigner par l’invisible Texte imprimé enquête sur les guérisseurs aujourd’hui
Imago, Auzas (2005)[22] D. Tomlinson, T. Hesser, M.C. Ethier, L. Sung
Complementary and alternative medicine use in pediatric cancer reported during palliative phase of disease
Support Care Cancer, 19 (11) (2011), pp. 1857-1863[23] M. Miller, M.J. Boyer, P.N. Butow, M. Gattellari, S.M. Dunn, A. Childs
The use of unproven methods of treatment by cancer patients
Support Care Cancer, 6 (4) (1998), pp. 337-347[24] M.M. Lee, S.S. Lin, M.R. Wrensch, S.R. Adler, D. Eisenberg
Alternative therapies used by women with breast cancer in four ethnic populations
JNCI J. Natl. Cancer Inst., 92 (1) (2000), pp. 42-47[25] B.M. Gulluoglu, A. Cingi, T. Cakir, A. Barlas
Patients in Northwestern Turkey prefer herbs as complementary medicine after breast cancer diagnosis
Breast Care, 3 (4) (2008), pp. 269-273[26] C.L. McDermott, D.K. Blough, C.R. Fedorenko, N.K. Arora, S.B. Zeliadt, M.E. Fairweather, et al.
Complementary and alternative medicine use among newly diagnosed prostate cancer patients
Support Care Cancer, 20 (1) (2012), pp. 65-73[27] A.H. Lee, S.E. Ingraham, M. Kopp, M.I. Foraida, A.R. Jazieh
The incidence of potential interactions between dietary supplements and prescription medications in cancer patients at a veterans administration hospital
Am. J. Clin. Oncol., 29 (2) (2006), p. 178[28] K.M. Kelly, J.S. Jacobson, D.D. Kennedy, S.M. Braudt, M. Mallick, M.A. Weiner
Use of unconventional therapies by children with cancer at an urban medical center
J. Pedia Hematol. Oncol., 22 (5) (2000), pp. 412-416[29] Bocquel C. Cancer du sein et soins de support: prise en charge des effets indésirables par les médecines complémentaires [Internet] [PhD Thesis]. 2016. Available at: 〈https://dumas.ccsd.cnrs.fr/dumas-01304454〉.
[30] Glaser B.G., Strauss A.L. The discovery of grounded theory strategies for qualitative research. New Brunswick, N.J.: Aldine Transaction; 1967.
[31] D. Pérol, J. Provençal, A. claire Hardy-Bessard, D. Coeffic, J.P. Jacquin, C. Agostini, et al.
Can treatment with Cocculine improve the control of chemotherapy-induced emesis in early breast cancer patients? A randomized, multi-centered, double-blind, placebo-controlled Phase III trial
BMC Cancer DéC., 12 (1) (2012), p. 603[32] J.C. Karp, C. Sanchez, P. Guilbert, W. Mina, A. Demonceaux, H. Curé
Treatment with Ruta graveolens 5CH and Rhus toxicodendron 9CH may reduce joint pain and stiffness linked to aromatase inhibitors in women with early breast cancer: results of a pilot observational study
Homeopathy, 105 (4) (nov 2016), pp. 299-308[33] E.A. Thompson, A. Montgomery, D. Douglas, D. Reilly
A pilot, randomized, double-blinded, placebo-controlled trial of individualized homeopathy for symptoms of estrogen withdrawal in breast-cancer survivors
févr – J. Altern. Complement. Med., 11 (1) (2005), pp. 13-20[34] C. Buettner, C.H. Kroenke, R.S. Phillips, R.B. Davis, D.M. Eisenberg, M.D. Holmes
Correlates of use of different types of complementary and alternative medicine by breast cancer survivors in the nurses’ health study
Breast Cancer Res. Treat., 100 (2) (1 nov 2006), pp. 219-227[35] L.K. Helyer, S. Chin, B.K. Chui, B. Fitzgerald, S. Verma, E. Rakovitch, et al.
The use of complementary and alternative medicines among patients with locally advanced breast cancer – a descriptive study
BMC Cancer 21 Févr, 6 (1) (2006), p. 39[36] T. Kremser, A. Evans, A. Moore, K. Luxford, S. Begbie, A. Bensoussan, et al.
Use of complementary therapies by Australian women with breast cancer
Breast 1 août, 17 (4) (2008), pp. 387-394[37] J. Shen, R. Andersen, P.S. Albert, N. Wenger, J. Glaspy, M. Cole, et al.
Use of complementary/alternative therapies by women with advanced-stage breast cancer
BMC Complement. Altern. Med. 13 août, 2 (1) (2002), p. 8[38] R. Moschèn, G. Kemmler, H. Schweigkofler, B. Holzner, M. Dünser, R. Richter, et al.
Use of alternative/complementary therapy in breast cancer patients–a psychological perspective
Support Care Cancer juin, 9 (4) (2001), pp. 267-274[39] C.C. Hack, S. Antoniadis, J. Hackl, H. Langemann, J. Schwitulla, P.A. Fasching, et al.
Breast cancer patients’ satisfaction with individual therapy goals and treatment in a standardized integrative medicine consultancy service
Arch. Gynecol. Obstet., 298 (1) (2018), pp. 147-156[40] C. Lévi-Strauss
La pensée sauvage
Plon, Paris (1962)[41] J. Phillimore, T. Brand, H. Bradby, B. Padilla
Healthcare bricolage in Europe’s superdiverse neighbourhoods: a mixed methods study
BMC Public Health, 19 (1) (2019), p. 1325[42] Cohen P., Rosi I., Sarradon A., Schmitz O. Des systèmes pluriels de recours non conventionnels des personnes atteintes de cancer: Une approche socioanthropologique comparative (France, Belgique, Suisse) [Internet]. 2010 [2023-07-21]. Available at: 〈https://hal.science/hal-00763219〉.
[43] M. Verhoef, L. Weeks, A. Brazier, A. Leis
Evaluating supportive cancer care: are we missing an opportunity?
Support Care Cancer, 15 (8) (2007), pp. 905-907[44] M.A. Richardson, T. Sanders, J.L. Palmer, A. Greisinger, S.E. Singletary
Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology
J. Clin. Oncol., 18 (13) (2000), pp. 2505-2514[45] I.J. Lerner, B.J. Kennedy
The prevalence of questionable methods of cancer treatment in the United States
CA: A Cancer J. Clin., 42 (3) (1992), pp. 181-191[46] C. Brami, O. Bouché, J.C. Karp, H. Curé
La cancérologie intégrative ou l’utilisation des thérapies complémentaires. À propos d’un modèle américain
Bull. du Cancer, 101 (6) (2014), pp. 531-532[47] E. Rossi, C. Noberasco, Homeopathic Clinic, Campo di Marte Hospital, Local Health Unit Tuscany North West, Lucca, Italy, Picchi M, Homeopathic Clinic, Campo di Marte Hospital, Local Health Unit Tuscany North West, Lucca, Italy, M. Di Stefano, et al.
Homeopathy and complementary integrative medicine, dietary and lifestyle advices to reduce adverse-effects of anti-cancer therapy: a cohort study with breast cancer patients
Obm Icm, 3 (3) (2018), p. 1[48] T. Kremser, A. Evans, A. Moore, K. Luxford, S. Begbie, A. Bensoussan, et al.
Use of complementary therapies by Australian women with breast cancer
Breast, 17 (4) (2008), pp. 387-394[49] B. Gerber, C. Scholz, T. Reimer, V. Briese, W. Janni
Complementary and alternative therapeutic approaches in patients with early breast cancer: a systematic review
Breast Cancer Res. Treat., 95 (3) (2006), pp. 199-209[50] J. Huebner, F.J. Prott, O. Micke, R. Muecke, B. Senf, G. Dennert, et al.
Online survey of cancer patients on complementary and alternative medicine
Oncol. Res. Treat., 37 (6) (2014), pp. 304-308[51] E. Ben-Arye, E. Schiff, K. Mutafoglu, S. Omran, R. Hajjar, H. Charalambous, et al.
Integration of complementary medicine in supportive cancer care: survey of health-care providers’ perspectives from 16 countries in the Middle East
Support Care Cancer, 23 (9) (2015), pp. 2605-2612[52] E T, F M, A H, C G. Use of complementary and alternative medicine in breast cancer patients and their experiences: a cross-sectional study. European journal of cancer (Oxford, England: 1990) [Internet]. nov 2012 [2023-07-24];48(17). Disponible sur: 〈https://pubmed.ncbi.nlm.nih.gov/22633625/〉.
[53] D. Gupta, C.G. Lis, T.C. Birdsall, J.F. Grutsch
The use of dietary supplements in a community hospital comprehensive cancer center: implications for conventional cancer care
Support Care Cancer, 13 (11) (2005), pp. 912-919[54] E. Ernst Serious adverse effects of unconventional therapies for children and adolescents: a systematic review of recent evidence
Eur. J. Pedia, 162 (2) (2003), pp. 72-80[55] B. Niggemann, C. Grüber
Side-effects of complementary and alternative medicine
Allergy, 58 (8) (2003), pp. 707-716[56] A. Laengler, C. Spix, G. Seifert, S. Gottschling, N. Graf, P. Kaatsch
Complementary and Alternative Treatment Methods in Children with Cancer. A Population Based Retrospective Survey on the Prevalence of Use In Germany 1990 – European journal of cancer, 44, Oxford, England (2008), pp. 2233-2240[57] I. Hyodo, N. Amano, K. Eguchi, M. Narabayashi, J. Imanishi, M. Hirai, et al.
Nationwide survey on complementary and alternative medicine in cancer patients in Japan
JCO, 23 (12) (2005), pp. 2645-2654[58] E. Kang, E.J. Yang, S.M. Kim, I.Y. Chung, S.A. Han, D.H. Ku, et al.
Complementary and alternative medicine use and assessment of quality of life in Korean breast cancer patients: a descriptive study
Support Care Cancer, 20 (3) (2012), pp. 461-473[59] R.A. Al-Naggar, Y.V. Bobryshev, M. Abdulghani, S. Rammohan, M.T. Osman, S.Y. Kadir
Complementary/alternative medicine use among cancer patients in Malaysia. World
J. Med. Sci. (2013), pp. 157-164[60] N. Samuels, Y. Freed, R. Weitzen, M. Ben-David, Y. Maimon, U. Eliyahu, et al.
Feasibility of homeopathic treatment for symptom reduction in an integrative oncology service
Integr. Cancer Ther., 17 (2) (2018), pp. 486-492[61] F. Bosco, S. Cidin, F. Maceri, M. Ghilli, M. Roncella, L.D. Simone
An integrated approach with homeopathic medicine and electro-acupuncture in anaesthesiology during breast cancer surgery: case reports
J. Pharmacopunct., 21 (2) (2018), pp. 126-131[62] Médicaments homéopathiques: une efficacité insuffisante pour être proposés au remboursement [Internet]. Haute Autorité de Santé. [2023-07-21]. Available at: 〈https://www.has-sante.fr/jcms/p_3066934/fr/medicaments-homeopathiques-une-efficacite-insuffisante-pour-etre-proposes-au-remboursement〉.
[63] G.H. Lyman, K. Bohlke, L. Cohen
Integrative therapies during and after breast cancer treatment: ASCO endorsement of the SIO clinical practice guideline summary
JOP, 14 (8) (2018), pp. 495-499[64] J.Y. Shin, S.Y. Kim, B. Park, J.H. Park, J.Y. Choi, H.G. Seo, et al.
Predictors of complementary and alternative medicine use in cancer care: results of a nationwide multicenter survey in Korea
Evid. Based Complement. Altern. Med., 2012 (2012), Article e212386[65]
T. Behroozian, P. Bonomo, P. Patel, L. Kanee, S. Finkelstein, C. van den Hurk, et al.
Multinational Association of Supportive Care in Cancer (MASCC) clinical practice guidelines for the prevention and management of acute radiation dermatitis: international Delphi consensus-based recommendations
Lancet Oncol., 24 (4) (2023), pp. e172-e185[66] M.M. Hedderson, R.E. Patterson, M.L. Neuhouser, S.M. Schwartz, D.J. Bowen, L.J. Standish, et al.
Sex differences in motives for use of complementary and alternative medicine among cancer patients
Alter. Ther. Health Med., 10 (5) (2004), pp. 58-64[67] A.E. Kristoffersen, A.J. Norheim, V.M. Fønnebø
Complementary and alternative medicine use among norwegian cancer survivors: gender-specific prevalence and associations for use
Evid. Based Complement. Altern. Med., 2013 (2013), Article e318781[68] M.M. Lee, J.S. Chang, B. Jacobs, M.R. Wrensch
Complementary and alternative medicine use among men with prostate cancer in 4 ethnic populations
Am. J. Public Health, 92 (10) (2002), pp. 1606-1609
Comunicazione a cura di:
Centro di Salute Globale SIMOH
Scuola Italiana di Medicina Omeopatica Hahnemanniana
Via Giovanni Miani, 8 – 00154 Roma
www.omeopatiasimoh.org – info@omeopatiasimoh.net
